An in vitro study published in the Journal of Cardiovascular Pharmacology on the grape seed and skin extracts re-affirmed the beneficial effects of grape seed and extracts on health. Study researchers observed significant antioxidant and anti-thrombotic activity in human platelets incubated with grape seed and extracts. Researchers also concluded that grape seeds and extracts are an appropriate alternative source of flavanoids in light of potential adverse effects related to the consumption of wine. Future studies are warranted to determine mechanism of action and the components of grape that are responsible for the beneficial effects.
Source:J. Cardiovasc Pharmacol. 2005 Oct, 46(4):445-51.